OCT-based label-free in vivo lymphangiography within human skin and areola
Identifieur interne : 000D41 ( Main/Exploration ); précédent : 000D40; suivant : 000D42OCT-based label-free in vivo lymphangiography within human skin and areola
Auteurs : Utku Baran [États-Unis] ; Wan Qin [États-Unis] ; Xiaoli Qi [États-Unis] ; Goknur Kalkan [Turquie] ; Ruikang K. Wang [États-Unis]Source :
- Scientific Reports [ 2045-2322 ] ; 2016.
Abstract
Due to the limitations of current imaging techniques, visualization of lymphatic capillaries within tissue
Url:
DOI: 10.1038/srep21122
PubMed: 26892830
PubMed Central: 4759696
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">OCT-based label-free <italic>in vivo</italic> lymphangiography within human skin and areola</title><author><name sortKey="Baran, Utku" sort="Baran, Utku" uniqKey="Baran U" first="Utku" last="Baran">Utku Baran</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Bioengineering, University of Washington</institution>, Seattle, WA,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a2"><institution>Department of Electrical Engineering, University of Washington</institution>, Seattle, WA,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Qin, Wan" sort="Qin, Wan" uniqKey="Qin W" first="Wan" last="Qin">Wan Qin</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Bioengineering, University of Washington</institution>, Seattle, WA,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Qi, Xiaoli" sort="Qi, Xiaoli" uniqKey="Qi X" first="Xiaoli" last="Qi">Xiaoli Qi</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Bioengineering, University of Washington</institution>, Seattle, WA,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kalkan, Goknur" sort="Kalkan, Goknur" uniqKey="Kalkan G" first="Goknur" last="Kalkan">Goknur Kalkan</name><affiliation wicri:level="1"><nlm:aff id="a3"><institution>Department of Dermatology, Yıldırım Beyazıt University</institution>, Ankara,<country>Turkey</country></nlm:aff><country xml:lang="fr">Turquie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Wang, Ruikang K" sort="Wang, Ruikang K" uniqKey="Wang R" first="Ruikang K." last="Wang">Ruikang K. Wang</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Bioengineering, University of Washington</institution>, Seattle, WA,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">26892830</idno><idno type="pmc">4759696</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759696</idno><idno type="RBID">PMC:4759696</idno><idno type="doi">10.1038/srep21122</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">000959</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000959</idno><idno type="wicri:Area/Pmc/Curation">000959</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000959</idno><idno type="wicri:Area/Pmc/Checkpoint">000742</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000742</idno><idno type="wicri:Area/Ncbi/Merge">007F03</idno><idno type="wicri:Area/Ncbi/Curation">007F03</idno><idno type="wicri:Area/Ncbi/Checkpoint">007F03</idno><idno type="wicri:Area/Main/Merge">000D42</idno><idno type="wicri:Area/Main/Curation">000D41</idno><idno type="wicri:Area/Main/Exploration">000D41</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">OCT-based label-free <italic>in vivo</italic> lymphangiography within human skin and areola</title><author><name sortKey="Baran, Utku" sort="Baran, Utku" uniqKey="Baran U" first="Utku" last="Baran">Utku Baran</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Bioengineering, University of Washington</institution>, Seattle, WA,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a2"><institution>Department of Electrical Engineering, University of Washington</institution>, Seattle, WA,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Qin, Wan" sort="Qin, Wan" uniqKey="Qin W" first="Wan" last="Qin">Wan Qin</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Bioengineering, University of Washington</institution>, Seattle, WA,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Qi, Xiaoli" sort="Qi, Xiaoli" uniqKey="Qi X" first="Xiaoli" last="Qi">Xiaoli Qi</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Bioengineering, University of Washington</institution>, Seattle, WA,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kalkan, Goknur" sort="Kalkan, Goknur" uniqKey="Kalkan G" first="Goknur" last="Kalkan">Goknur Kalkan</name><affiliation wicri:level="1"><nlm:aff id="a3"><institution>Department of Dermatology, Yıldırım Beyazıt University</institution>, Ankara,<country>Turkey</country></nlm:aff><country xml:lang="fr">Turquie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Wang, Ruikang K" sort="Wang, Ruikang K" uniqKey="Wang R" first="Ruikang K." last="Wang">Ruikang K. Wang</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Bioengineering, University of Washington</institution>, Seattle, WA,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">Scientific Reports</title><idno type="eISSN">2045-2322</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Due to the limitations of current imaging techniques, visualization of lymphatic capillaries within tissue <italic>in vivo</italic> has been challenging. Here, we present a label-free high resolution optical coherence tomography (OCT) based lymphangiography (OLAG) within human skin <italic>in vivo</italic>. OLAG enables rapid (~seconds) mapping of lymphatic networks, along with blood vessel networks, over 8 mm x 8 mm of human skin and 5 mm x 5 mm of human areola. Moreover, lymphatic system’s response to inflammation within human skin is monitored throughout an acne lesion development over 7 days. The demonstrated results promise OLAG as a revolutionary tool in the clinical research and treatment of patients with pathologic conditions such as cancer, diabetes, and autoimmune diseases.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Muthuchamy, M" uniqKey="Muthuchamy M">M. Muthuchamy</name></author><author><name sortKey="Zawieja, D" uniqKey="Zawieja D">D. Zawieja</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sevick Muraca, E M" uniqKey="Sevick Muraca E">E. M. Sevick-Muraca</name></author><author><name sortKey="Kwon, S" uniqKey="Kwon S">S. 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Li</name></author><author><name sortKey="Wang, R K" uniqKey="Wang R">R. K. Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yin, X" uniqKey="Yin X">X. Yin</name></author><author><name sortKey="Chao, J R" uniqKey="Chao J">J. R. Chao</name></author><author><name sortKey="Wang, R K" uniqKey="Wang R">R. K. Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yousefi, S" uniqKey="Yousefi S">S. Yousefi</name></author><author><name sortKey="Qin, J" uniqKey="Qin J">J. Qin</name></author><author><name sortKey="Zhi, Z" uniqKey="Zhi Z">Z. Zhi</name></author><author><name sortKey="Wang, R K" uniqKey="Wang R">R. K. Wang</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Turquie</li><li>États-Unis</li></country></list><tree><country name="États-Unis"><noRegion><name sortKey="Baran, Utku" sort="Baran, Utku" uniqKey="Baran U" first="Utku" last="Baran">Utku Baran</name></noRegion><name sortKey="Baran, Utku" sort="Baran, Utku" uniqKey="Baran U" first="Utku" last="Baran">Utku Baran</name><name sortKey="Qi, Xiaoli" sort="Qi, Xiaoli" uniqKey="Qi X" first="Xiaoli" last="Qi">Xiaoli Qi</name><name sortKey="Qin, Wan" sort="Qin, Wan" uniqKey="Qin W" first="Wan" last="Qin">Wan Qin</name><name sortKey="Wang, Ruikang K" sort="Wang, Ruikang K" uniqKey="Wang R" first="Ruikang K." last="Wang">Ruikang K. Wang</name></country><country name="Turquie"><noRegion><name sortKey="Kalkan, Goknur" sort="Kalkan, Goknur" uniqKey="Kalkan G" first="Goknur" last="Kalkan">Goknur Kalkan</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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